Dr Andrea Bistrovic

Post Doctoral Researcher

Andrea obtained her PhD in organic medicinal chemistry from the University of Zagreb. During her PhD she was involved in the synthesis of novel purine isosteres as anticancer agents using eco-friendly synthetic approaches and was awarded with the L’Oréal-UNESCO fellowship “For Women in Science”. She joined the Fruk group in 2018 to work on the design of new nanovehicles as smart drug-delivery systems for the treatment of pancreatic cancer. She is a College Research Associates at Kings College, Cambridge and outside the lab, she likes to travel and explore new cultures.

Selected Publications

1. A. Bistrovic Popov, I. Stolić, L. Krstulović, M. C. Taylor, J. M. Kelly, S. Tomić, L. Tumir, M. Bajić, S. Raić-Malić, Novel symmetric bis-benzimidazoles: Synthesis, DNA/RNA binding and antitrypanosomal activity, Eur J Med Chem. 2019, 173, 63.

2. A. Bistrović, L. Krstulović, I. Stolić, D. Drenjančević, J. Talapko, M. C. Taylor, J. M. Kelly, M. Bajić, S. Raić-Malić, Synthesis, anti-bacterial and anti-protozoal activities of amidinobenzimidazole derivatives and their interactions with DNA and RNA, J Enyzme Inhib Med Chem. 2018, 33, 1323.

3. A. Bistrović, P. Grbčić, A. Harej, M. Sedić, S. Kraljević-Pavelić, S. Koštrun, J. Plavec, D. Makuc, S. Raić-Malić, Small molecule purine and pseudopurine derivatives: synthesis, cytostatic evaluations and investigation of growth inhibitory effect in non-small cell lung cancer A549, J Enyzme Inhib Med Chem. 2018, 33, 271.

4. A. Bistrović, A. Harej, P. Grbčić, M. Sedić, S. Kraljević Pavelić, M. Cetina, S. Raić-Malić, Synthesis and anti-proliferative effects of mono- and bis-purinomimetics targeting kinases, Int J Mol Sci. 2017, 18, 2292.

5. A. Bistrović, N. Stipaničev, T. Opačak-Bernardi, M. Jukić, S. Martinez, Lj. Glavaš-Obrovac and S. Raić-Malić, Synthesis of 4-aryl-1,2,3-triazolyl appended natural coumarin-related compounds with antiproliferative and radical scavenging activities and intracellular ROS production modification, New J Chem. 2017, 41, 7531.

6. S. Krištafor, A. Bistrović, J. Plavec, D. Makuc, T. Martinović, S. Kraljević Pavelić, S. Raić-Malić, One-pot click synthesis of 1,2,3-triazole embedded unsaturated uracil derivatives and hybrids of 1,5- and 2,5-disubstituted tetrazoles and pyrimidines, Tetrahedron Lett. 2015, 56, 1222.

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